Studies on transdermal absorption of isosorbide dinitrate tape.
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چکیده
منابع مشابه
Formulation and evaluation of transdermal drug-delivery system of isosorbide dinitrate
The purpose of this study was to develop a reservoir-type transdermal delivery system for isosorbide dinitrate (ISDN). The developed patch consisted of five layers from bottom to top, namely, a temporary liner, an adhesive layer, a rate-controlling membrane, a reservoir and a backing. The effects of chemical penetration enhancers, reservoir materials and rate-controlling membranes on the releas...
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The microcirculation appears to be impaired in cold chronic complex regional pain syndrome (CRPS). This double-blind, placebo-controlled, randomized trial investigated the effect of the nitric oxide (NO) donor isosorbide dinitrate (ISDN) on the peripheral blood flow in patients with chronic CRPS. Twenty-four patients received 1% ISDN in Vaseline or a placebo ointment applied to the dorsum of th...
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26. Bleifeld W, Mathey D, Hanrath P, Buss H, Effert S: Infarct size estimated from serial serum creatine phosphokinase in relation to left ventricular hemodynamics. Circulation 55: 303, 1977 27. Humphries JO, Pitt B, Griffith LSC, Ducci HH, Achuff S, Baird M, Schulze RA Jr: Coronary angiography and left ventriculography in survivors of transmural and subendocardial myocardial infarction. Circul...
متن کاملEvaluation of nitroglycerin in angina in patients on isosorbide dinitrate.
Seventeen male patients with angina pectoris due to coronary artery disease who had not received long-acting nitrites for at least 1 mo prior to this study were evaluated in a double-blind crossover study to investigate whether the presence of isosorbide dinitrate interfered with the effective response of exercise-induced angina to nitroglycerin administered sublingually. There was no significa...
متن کاملVasodilator properties of nitroglycerin and isosorbide dinitrate during cardiopulmonary bypass.
In a placebo-controlled trial, we have studied the vasodilator properties of bolus doses of nitroglycerin (TNG) and isosorbide dinitrate (ISDN) in 32 patients during cardiopulmonary bypass with a constant pump flow. Blood volume of the venous reservoir and mean arterial pressure were recorded for 10 min after drug administration to detect changes in venous capacitance and arteriolar resistance,...
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ژورنال
عنوان ژورنال: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
سال: 1987
ISSN: 1882-8272,0388-1601
DOI: 10.3999/jscpt.18.627